Transretinoic acid inhibits rats gastric epithelial dysplasia induced by N-methyi-N-nitro-N-nitrosoguanidine:influences on cell apoptosis and expression of its regulatory genes  

作　　者：Ru Tao Cui Gan Cai Zhao Bao Yin Yong Cheng Qiu Hong Yang Tao Tian 

机构地区：[1]Liver Center,Beijing Friendship Hospital Affiliated to CapitalUniversity of Medical Sciences [2]Department of Gastroenterology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai China,Department of Pathophysiology.Shanghai Medical University.Shanghai,China [3]Pathological Department,Shanghai Medical University

出　　处：《World Journal of Gastroenterology》2001年第3期394-398,共5页世界胃肠病学杂志(英文版)

基　　金：Supported by the Science Fund of Health Department,No.95A2141.and the Science Fund of Health Bureau of Shanghai.No.982019

摘　　要：INTRODUCTIONGastric epithelial dysplasia (GED) hypothetically is a straight-forward concept: dysplastic epithelium replacing the normal gastric epithelium of the stomach [1].In the stomach ,like any other segment of the gut ,it is defined as an unequivocal non-invasive epithelial change[2,3].The observation of gastric dysplasia as a cancerous lesion was recognized over a century ago ,but it is only after the advent of gastroscopy that its clinical significance has been stressed[4-7].

关 键 词：Animals Antigens  CD95 Antineoplastic Agents Apoptosis Caspase 1 Cyclin D1 Gastric Mucosa Gene Expression Immunohistochemistry Male Membrane Glycoproteins METHYLNITRONITROSOGUANIDINE RNA  Messenger RATS Rats  Wistar Research Support  Non-U.S. Gov't Stomach Diseases TRETINOIN 

分 类 号：R573.9[医药卫生—消化系统]