枳实、枳壳中辛弗林含量比较分析  

Comparative analysis of synephrine content in Fructus Aurantii Immaturus and Fructus Aurantii

作　　者：黄伟[1] 刘友平[1] 赵祎姗[1] 施学骄[1] 张杰红[1] 彭月[1] 

机构地区：[1]成都中医药大学药学院中药材标准化教育部重点实验室中药资源系统研究与开发利用省部共建国家重点实验室培育基地,四川成都610075

出　　处：《中药与临床》2011年第3期21-23,35,共4页Pharmacy and Clinics of Chinese Materia Medica

基　　金：四川省教育厅自然科学重点项目(NO.09ZA033);国家自然科学基金项目(NO.81072991)

摘　　要：目的:比较枳实、枳壳中辛弗林的含量差异,为枳实、枳壳类药材质量控制提供科学依据。方法:采用高效液相色谱法,测定14批枳实、枳壳药材(8批枳壳,6批枳实)中辛弗林的含量。结果:枳实、枳壳药材中辛弗林含量有明显差异,枳实辛弗林含量明显高于枳壳。同产地枳实、枳壳中辛弗林含量差异较大。结论:枳实、枳壳类药材中辛弗林含量差异较大,应建立含辛弗林类药材的质量标准,为临床用药安全有效提供科学依据。Objective:To compare the contents of synephrine in Fructus Aurantii Immaturus and Fructus Aurantii,and support the scientific basis for quality control of the medicines.Method:HPLC was used to detect the contents of synephrine of eight batches of Fructus Aurantii and six batches of Fructus Aurantii Immaturus.Result:There were obvious differences between Fructus Aurantii Immaturus and Fructus Aurantii in synephrine contents,which in Fructus Aurantii Immaturus were higher than Fructus Aurantii.The synephrine contents of Fructus Aurantii Immaturus and Fructus Aurantii were quite different from different areas.Conclusion:The synephrine content has significant difference between Fructus Aurantii Immaturus and Fructus Aurantii.The quality standards of synephrine herbs should be built to provide scientific basis for safe and effective application in clinic.

关 键 词：枳实 枳壳 辛弗林 高效液相色谱法 

分 类 号：R[医药卫生]