硬腭黏膜移植修复眼睑后层缺损的疗效观察  

Outcomes of reconstruction of posterior eyelid defect with hard palate mucosa grafts

作　　者：朱惠敏[1] 李政康[1] 孙英[1] 范先群[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院眼科,上海200011

出　　处：《上海交通大学学报（医学版）》2011年第8期1065-1068,共4页Journal of Shanghai Jiao tong University:Medical Science

基　　金：上海市重点学科建设项目(S30205)~~

摘　　要：目的观察硬腭黏膜移植修复眼睑后层(睑板结膜)缺损的效果及安全性。方法回顾性分析17例接受自体硬腭黏膜移植修复的眼睑后层缺损患者的临床及随访资料。17例患者中,男性10例(10眼),女性7例(7眼),年龄21~79岁;眼睑肿瘤切除术后一期修复10例,化学伤后眼睑内翻倒睫2例,外伤后眼睑缺损3例,结膜囊成形术佩戴义眼片后眼睑退缩2例;上睑缺损9例,下睑缺损8例。术后随访检查指标包括眼睑的形态、角膜刺激症状及裂隙灯下观察角膜上皮等。结果病例术后随访3个月至3年。随访结果显示:所有患者眼睑形态良好;接受下睑缺损修复者术后无明显不适;接受上睑缺损修复的部分患者术后早期可有眼部充血、异物感等不适症状,裂隙灯检查可见角膜上皮脱落,经局部对症治疗后症状逐渐消失。结论硬腭黏膜具有完整的黏膜上皮组织及与睑板相似的坚韧度,可有效修复眼睑后层的缺损,且对下睑有良好的支撑作用。Objective To observe the effects and safety of reconstruction of posterior eyelid(tarsal conjunctiva) defect with hard palate mucosa grafts. Methods The clinical and follow-up data of 17 patients with posterior eyelid defect undergoing construction with autologous hard palate mucosa grafts were retrospectively analysed.Among the 17 patients,10 were males(10 eyes),the other 7 were females(7 eyes),and all patients aged between 21 to 79 years.Ten cases were caused by eyelid tumor,2 by chemical damage,3 by trauma and 2 by eyelid retraction after socket reconstruction.There were 9 cases of upper eyelid defect and 8 cases of lower eyelid defect.During the follow up,the appearance of eyelid and the corneal irritation symptoms were observed,and the corneal epithelium was observed under slit lamp. Results Patients were followed up for 3 months to 3 years.All patients had an ideal appearance of eyelid.There was no discomfort in patients with construction of lower eyelid defect.Some patients with construction of upper eyelid defect suffered from conjunctival congestion and foreign body sensation,and corneal abrasion was observed under slit lamp.These symptoms disappeared after local symptomatic treatment. Conclusion Hard palate mucosa has intact epithelial tissues and similar toughness to tarsus,can provide an effective reconstruction of posterior eyelid defect,and has a good effect to support the lower eyelid.

关 键 词：眼睑缺损 硬腭黏膜 移植 

分 类 号：R779.6[医药卫生—眼科]