垂体转移癌的诊断和处理  

Diagnosis and treatment of pituitary metastases

作　　者：高俊[1] 关健[1] 王国华 杜世伟[1] 霍真[3] 杨义[1] 王任直[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院神经外科,100730 [2]潍坊市立医院神经外科,261021 [3]中国医学科学院北京协和医学院北京协和医院病理科,100730

出　　处：《中国微侵袭神经外科杂志》2011年第4期165-167,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的总结垂体转移癌的治疗经验。方法回顾性分析8例经病理确诊为垂体转移癌病人的临床资料。临床表现包括尿崩6例,动眼神经麻痹4例。行经蝶窦手术6例,开颅手术2例。结果肿瘤次全切除2例,大部分切除3例,部分切除3例。术后生存期30~260 d,平均151 d。结论垂体转移癌为罕见鞍区恶性肿瘤,手术可明确病理诊断及缓解临床症状。术后需综合治疗,同时积极寻找原发灶。Objective To review the experience in treatment of pituitary metastases.Methods The clinical data of 8 patients with pituitary metastases who were diagnosed by pathological examination were analyzed retrospectively.The main symptoms included diabetes insipidus in 6 patients and oculomotor paralysis in 4.Transsphenoidal surgery was performed in 6 patients and craniotomy in 2.Results Subtotal removal of the tumor was achieved in 2 patients,major removal in 3 and partial removal in 3.The survival period ranged from 30 to 260 d with the mean of 151 d.Conclusions Pituitary metastatic cancer is a rare malignant tumor in the sella region.Pathologic diagnosis and the relief of symptoms can be made by surgery.Comprehensive therapy is necessary after surgery and at the same time primary focus should be detected actively.

关 键 词：垂体肿瘤 转移癌 诊断 治疗 

分 类 号：R736.4[医药卫生—肿瘤]