胸部CT对重症肌无力患者胸腺病变的诊断价值  

Diagnostic value of computed tomography on thymic pathology complicated by myasthenia gravis

作　　者：许国宇[1] 窦云轲 袁小东[1] 敖国昆[1] 乔远罡[1] 

机构地区：[1]解放军第309医院放射科,北京100091 [2]重症肌无力中心

出　　处：《中华临床医师杂志（电子版）》2011年第23期6918-6921,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨胸部CT对重症肌无力患者胸腺病变的诊断价值。方法回顾性分析137例重症肌无力患者的胸腺CT影像及病理资料,分析CT影像及病理结果有无关联性。结果 137例重症肌无力患者胸腺异常共125例,占91.24%。CT诊断胸腺病变敏感度为86.40%,特异度为83.33%,准确度为86.13%,CT诊断结果和病理结果进行一致性检验:Kappa=0.427,P<0.001。结论 CT发现和诊断胸腺病变敏感度准确度较高,是诊断重症肌无力患者胸腺病变的较好方法。Objective To determine the diagnostic value of computed tomography(CT) on thymic pathological changes complicated by myasthenia gravis.Methods CT images and pathological documents of 137 cases of myasthenia gravis were investigated retrospectively.The agreement between CT and pathological findings was obtained by Kappa test.The accuracy of CT diagnosis was calculated.Results Totally 125 thymic pathology(91 thymus hyperplasia,34 thymoma) were confirmed pathologically.A Kappa value of 0.427(P<0.001) was derived from Kappa test.CT was demonstrated sensitivity of 86.40%,specificity of 83.33%,and accuracy of 86.13% for detecting thymic pathological changes.Conclusions CT is of high value in detecting thymic pathological changes complicated by myasthenia gravis.

关 键 词：胸腺瘤 胸腺增生 重症肌无力 体层摄影术 X线计算机 

分 类 号：R746.1[医药卫生—神经病学与精神病学]