卵巢外腹膜浆液性乳头状癌3例临床及预后分析  

Clinic and prognostic analysis on three cases of extraovarin peritoneal serous papillary carcinoma(EPSPC)

作　　者：鲁永鲜[1] 刘静霞[1] 张琳[1] 胡蔓萝[1] 沈文洁[1] 刘昕[1] 陆江阳[2] 

机构地区：[1]解放军第304医院妇产科,北京100037 [2]解放军第304医院病理科

出　　处：《感染．炎症．修复》2003年第2期75-77,共3页Infection Inflammation Repair

摘　　要：目的:探讨如何提高卵巢外腹膜浆液性乳头状癌(EPSPC)的临床诊断率及疗效。方法:对3例EPSPC的临床资料进行回顾性分析。结果:3例患者经过临床、B超及肿瘤标记物的检查后,均在术前做出了诊断。在一个疗程的先期化疗后,3例患者接受了肿瘤细胞减灭术及含铂类药物的联合化疗2～9个疗程。除1例失访外,其余2例病情得到完全控制,至今无复发迹象。1例已存活78个月,另一例20个月。结论:通过早期诊断,实施彻底的肿瘤细胞减灭术,术后及时给予足量含铂类药物的联合化疗,可显著改善EPSPC患者的预后。To investigate how to improve the clinic diagnosis and treatment of extraovarin peritoneal serous pspillary carcinoma (EPSPC). Methods: A retrospective study was analyzed from 3 cases of EPSPC. Re suits:All cases of the patients were correctly diagnosed as EPSPC before operation through clinic, utrasound and tumor marker examinations. After one cycle of neoadjuvant chemotherapy, cytoreductive surgery and the com bined chemotherapy with Platinum and Cyclophosphamide were performed on all patients. After operation 3 pa tients had received 2-9 courses of combined chemotherapy with Platinum respectively. Except one patient lost fol low-up after 2 courses of chemotherapy, the other two were still survived with no clinic signs of recurrence. One patient had already been living for 78 monthes, the other for 20 monthes. Conlusions: By early diagnosis, com pletely cytoreductive surgery and combined chemotherapy including platinum agent,patients' prognosis can be im proved markedly.

关 键 词：卵巢外腹膜浆液性乳头状癌 临床治疗 预后 

分 类 号：R737[医药卫生—肿瘤]