单纯地西泮与地西泮联合丙戊酸治疗癫持续状态的疗效比较  

Efficacy comparison of diazepam and diazepam combined with valproate on status epilepticus

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作  者:刘渊华[1] 王勤鹰[1] 詹青[1] 

机构地区:[1]上海市同济医院神经重症监护室,上海200065

出  处:《神经病学与神经康复学杂志》2011年第3期125-126,133,共3页Journal of Neurology and Neurorehabilitation

摘  要:目的比较单纯地西泮和地西泮联合丙戊酸钠治疗癫持续状态(SE)的疗效。方法选择成人SE患者35例,分成地西泮组(给予地西泮静脉治疗)和地西泮联合丙戊酸钠组(地西泮联合丙戊酸钠静脉治疗)两组,观察两组的疗效。结果两组治疗的有效率差异无统计学意义,地西泮联合丙戊酸钠组72 h内复发率低于地西泮组(P<0.05)。结论地西泮联合丙戊酸钠治疗可降低SE患者的复发。Objective To compare the efficacy of diazepam and diazepam combined with valproate on status epilepticus(SE).Methods Thirty-five patients with SE in adults were enrolled and devided into two groups,the diazepam group(given diazepam injection) and the diazepam combined with valproate group(given diazepam and valproate injection),the efficacy of the two groups were observed.Results There was no significant difference of the efficiency between the two groups.The recurrent rate in the diazepam combined with valproate group within 72 h was lower than that in the diazepam group(P<0.05).Conclusion The treatment of diazepam combined with valproate can lessen the recurrence of SE.

关 键 词:癫持续状态 地西泮 丙戊酸钠 疗效 

分 类 号:R742.1[医药卫生—神经病学与精神病学] R741.05[医药卫生—临床医学]

 

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