甲钴胺治疗小纤维神经病临床观察  

Observation of the effect of methylcobalamin on patients with small fiber neuropathies

作　　者：林智[1] 李建萍[1] 

机构地区：[1]上海交通大学医学院附属仁济医院神经内科,上海200127

出　　处：《神经病学与神经康复学杂志》2010年第1期32-34,共3页Journal of Neurology and Neurorehabilitation

摘　　要：目的观察甲钴胺对小纤维神经病的疗效。方法对28例小纤维神经病患者进行临床观察。治疗组以甲钴胺500μg肌注,每日1次,2周后改为每周3次,共治疗3月。对照组以甲钴胺500μg肌注,每日1次,2周后停药。结果治疗组的神经病变主觉症状问卷(TSS)评分(1.02±0.87)较对照组(2.11±0.93)明显减少。结论甲钴胺对小纤维神经病可能有效。Objective To observe the effect of methylcobalamin on patients with small fiber neuropathies.Methods Twenty-eight patients with small fiber neuropathies were recruited and equally divided into two groups.Half of them were treated with methylcobalamin 500 μg intramuscularly once a day for two weeks,then followed by 500 ug intramuscularly three times a week for 10 weeks.The other half of patients were treated with methylcobalamin 500 ug intramuscularly once a day for two weeks and served as controls.Results After 3-month,the mean value of Total Symptoms Score from treated patients was lower than that from controls(1.02±0.85 vs 2.11±0.93).Conclusion Methylcobalamin may be effective for treatment of small fiber neuropathies.

关 键 词：周围神经病 甲钴胺 治疗 

分 类 号：R741[医药卫生—神经病学与精神病学]