氟桂利嗪对低ABCD^2评分的短暂性缺血发作患者的脑梗死预防作用  

Prevention of ischemic stroke by flunarizine among transient ischemic attack patients with low ABCD^2 scores

作　　者：王向明[1] 陶庆玲[1] 龚毓华 廖小平 

机构地区：[1]上海市长宁区中心医院神经内科,上海200336 [2]上海市嘉定区安亭医院内科,上海201805

出　　处：《神经病学与神经康复学杂志》2010年第4期199-201,共3页Journal of Neurology and Neurorehabilitation

摘　　要：目的探讨氟桂利嗪对低危短暂性缺血发作(TIA)患者脑梗死的预防作用。方法按照ABCD2的评分标准,将126例评分为1～3分的低危患者随机分成治疗组和对照组。治疗组在常规治疗的基础上给予氟桂利嗪。比较两组治疗对脑梗死发病的预防效果。结果治疗组在90 d内的脑梗死发生率为1.6%,明显低于对照组的12.6%(P<0.05),且无不良反应。结论氟桂利嗪可降低低危TIA患者的脑梗死发生风险。Objective To observe the effect of flunarizine for prevention of ischemic stroke among transient ischemic attack(TIA) patients with low ABCD2 scores. Methods One hundred and twenty-six TIA patients with the ABCD2scores of 1-3 were randomly divided into the treatment group and the control group.The patients in the treatment group were given flunarizine on the basis of standard stroke prevention therapy.The incidences of recent ischemic stroke were compared between two groups. Results The incidence of ischemic stroke within 90 days was 1.6% in the treatment group,which was lower than 12.6% in the control group. Conclusion Flunarizine may reduce the risk of recent ischemic stroke in TIA patients with low ABCD2 score.

关 键 词：短暂性脑缺血发作 氟桂利嗪 脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]