2-氨基-6-二茂铁基-4-(2,4-二氯苯基)吡啶-3-腈类化合物的微波合成和结构表征  

Synthesis of 2-amino-6-ferrocenyl-4-(2,4-dichlorophenyl) pyridine-3-carbonitrile under microwave irradiation and its crystal structure

作　　者：贾润红[1] 彭菊花[1] 屠树江[2] 

机构地区：[1]连云港师范高等专科学校初等教育系,江苏连云港222006 [2]徐州师范大学化学化工学院,江苏徐州221116

出　　处：《河北科技大学学报》2012年第1期6-10,13,共6页Journal of Hebei University of Science and Technology

基　　金：国家自然科学基金资助项目(20672090);江苏省自然科学基金资助项目(BK2006033)

摘　　要：标题化合物C24H20Cl2FeN2O2是由2,4-二氯苯甲醛、乙酰二茂铁、氰乙酸乙酯、醋酸铵在水相中微波辐射下反应制得。结构通过单晶X射线衍射法测定,其晶体属单斜晶系、空间群P21/n,a=0.749(3)nm,b=1.136(3)nm,c=2.577(3)nm,α=γ=90°,β=94.021(2)°,V=2.188(1)nm3,相对分子质量Mr=495.17,晶胞密度Dc=1.503g/cm3,Z=4,λ=0.071 073nm,吸收系数μ(Mo Kα)=0.958mm-1,F(000)=1 016,最终偏离因子R=0.079 7,wR=0.161 6。The title compound C24H20Cl2FeN2O2 was synthesized by the reaction of 2,4-dichlorobenzaldehyde,acetylferrocene,ethyl cyanoacetate,and ammonium acetate in aqueous medium under microwave irradiation.Its crystal structure was determined by single-crystal X-ray diffraction.The crystal is of monoclinic and space group P21/n,a=0.749(3) nm,b=1.136(3) nm,c=2.577(3) nm,α=γ=90°,β=94.021(2)°,V=2.188(1) nm3,Mr =495.17,Dc=1.503 g/cm3,Z=4,λ=0.071 073 nm,μ(Mo Kα)=0.958 mm-1,F(000) =1 016,R=0.079 7,and wR=0.161 6.

关 键 词：微波辐射 二茂铁取代吡啶 晶体结构 

分 类 号：O62[理学—有机化学]