大鼠前牙扭转移动后保持期动物模型的建立  

Establishment of rat retention model in incisors

作　　者：崔淑霞[1] 朱凤节[1] 

机构地区：[1]郑州大学口腔医学院正畸科,河南郑州450052

出　　处：《西安交通大学学报（医学版）》2011年第6期787-789,共3页Journal of Xi’an Jiaotong University（Medical Sciences）

基　　金：郑州市二七区科技局基金资助项目(No.20103373)~~

摘　　要：目的建立大鼠实验性正畸前牙扭转移动后保持期的动物模型并分析保持时间与复发距离的关系。方法采用36只雌性SD大鼠,在上颌两个中切牙间施加20g的力量,建立牙根扭转的动物模型。10d后进行固定保持,分为1、4、7、14、21d保持组(实验组),并设不予保持的对照组。测量加力结束后、保持结束时和拆除保持器后7d两中切牙之间的距离变化。计算每组大鼠拆除保持器7d后的复发距离(M)。复发距离(M)=保持结束后两切牙之间的距离(M1)-复发7d后两切牙中间的距离(M2)。结果各实验组复发距离分别为(1.95±0.30)、(0.84±0.06)、(0.69±0.03)、(0.32±0.10)、(0.09±0.04)mm,明显小于对照组(2.57±0.08)mm,差异有统计学意义(P<0.05)。结论正畸用直径0.25mm结扎丝可以用作固定保持器来建立大鼠前牙扭转移动后保持期的动物模型。Objective To establish an experimental orthodontic movement of anterior teeth in rats and analyze the relationship between retention duration and relapse distance.Methods Totally 36 female SD rats were provided for the experiment and divided into 6 groups with 6 rats in each.Maxillary central incisors were anchored to each other and a continuous force of 20 g was applied for 10 days so as to rotate the root of both the maxillary incisors in the animal models.After the rotation was completed,orthodontic ligation wire of a diameter of 0.25 mm was used to retain the tooth in rotated position.Rats in each group were maintained to continue retention for 1,4,7,14 and 21 days respectively and the retention wire was removed,but in the control group no retention was done.The distance between the two maxillary central incisors was measured after 7 days of removal of appliances.The effectiveness of devices for retention was studied by the relationship between duration of maintaining retention appliance and the relapse of tooth movement distance and calculated as the distance difference of tooth and length of ligation wire used for retention.Results Post-retention distance in each experimental group was(1.95±0.30),(0.84±0.06),(0.69±0.03),(0.32±0.10) and(0.09±0.04)mm,which was significantly less than that in the control group(2.57±0.08)mm(P<0.05).Conclusion Orthodontic ligature wire with a diameter of 0.25mm can be used as a fixed retainer to keep the anterior teeth to avoid relapse after orthodontic tooth movement in rats for the retention period in the animal model.

关 键 词：扭转牙 前牙扭转移动后保持 正畸 牙根扭转动物模型 复发距离 大鼠 

分 类 号：R783.5[医药卫生—口腔医学]