苯甲醛缩氨基硫脲类化合物的无溶剂合成  

olvent-free Synthesis of Benzaldehyde Thiosemicarbazone Derivatives

作　　者：冯文成[1] 周艳青[1] 尚秀丽[1] 

机构地区：[1]兰州石化职业技术学院,甘肃兰州730060

出　　处：《辽宁化工》2012年第7期645-646,共2页Liaoning Chemical Industry

基　　金：甘肃省省属高校基本科研业务费资助项目;项目号:甘财教(2009-192);兰州石化职业技术学院科研项目;项目号:K07-3

摘　　要：以苯甲醛和2-羟基苯甲醛与N4-苯基氨基硫脲为原料,浓盐酸做催化剂,室温条件下,在无溶剂条件下进行反应合成了2个缩氨基硫脲类化合物。产品经元素分析、红外光谱与核磁共振氢谱表征,确定为目标化合物。结果表明,无溶剂条件下的反应在2 h内产率达到90%,是合成该类化合物高产、低耗、绿色、环保的好方法。Using concentrated hydrogen chloride(HCl) as the catalyst,two kinds of thiosemicarbazone derivatives were synthesized from benzaldehyde,o-hydroxybenaaldehyde and 4-phenylthiosemicarbazide under solvent-free condition at room temperature.The structure of these compounds were characterized by elemental analysis,IR and 1HNMR.The results show that the yield of the product can reach 90% when reaction time is 2h;the solvent-free synthesis method has many advantages for the synthesis of this kind of fine chemicals,such as high yield,low consumption and environmental protection.

关 键 词：苯甲醛 缩氨基硫脲 无溶剂合成 

分 类 号：TQ2[化学工程—有机化工]