彩超水囊引导下A型肉毒毒素治疗慢性偏头痛  

Botulinum Toxin Type A Injection Under Color Ultrasound with Water Capsule Guidance for Treatment of Chronic Migraine

作　　者：宋金辉[1] 丁旭东[1] 肖红琼[1] 黄瓅[1] 张贵斌[1] 

机构地区：[1]湖北医药学院附属襄阳医院神经内科,湖北襄阳441000

出　　处：《湖北医药学院学报》2012年第1期25-28,共4页Journal of Hubei University of Medicine

摘　　要：目的:观察彩超水囊引导下A型肉毒毒素治疗慢性偏头痛的临床疗效和不良反应。方法:选取64例慢性偏头痛患者应用彩超水囊引导下A型肉毒毒素进行颅周肌肉注射治疗,记录患者治疗前后偏头痛发作频率、持续时间、严重程度、止痛药使用情况及恢复状况,并行VAS、MIDAS及SF-36评分。结果:所有患者经彩超水囊引导下A型肉毒毒素治疗后,慢性偏头痛发作频率、持续时间、严重程度均较治疗前明显下降(P<0.01),止痛药物的使用较治疗前减少(P<0.01),疗效可维持至少3月,且不良反应轻微。结论:彩超水囊引导下A型肉毒毒素颅周肌肉注射治疗慢性偏头痛发作临床疗效显著,不良反应轻微,值得临床推广。Objective To observe the clinical efficacy and safety of local injection of botulinum toxin A(BTX-A) under color ultrasound with water capsule guidance in patients with chronic migraine(CM).Methods Sixty-four patients with CM were treated with BTX-A under color ultrasound and water capsule guidance.The frequency,duration and severity of CM,medication usage of painkiller as well as side effects in patients with CM were recorded by the use of questionnaire,and were compared before and 6 months after treatment.Results Compared with those before treatments,the frequency,duration and severity of CM in patients at 6 month after treatment of BTX-A under color ultrasound and water capsule guidance were reduced significantly(P<0.01),and so were the frequency of medication usage of painkiller and the side effects.The therapeutic effects could last for at least 3 months.Conclusion BTX-A under color ultrasound and water capsule guidance has therapeutic effects on CM with few side effects.

关 键 词：彩色超声 水囊 慢性偏头痛 A型肉毒毒素 

分 类 号：R747.2[医药卫生—神经病学与精神病学]