双重引导下注射A型肉毒毒素治疗脑卒中肌肉痉挛  

Treatment of Stroke Spasm with Type A Botulinum Toxin Injection under Double Guidance

作　　者：丁旭东[1] 陈华先[1] 汪伟[1] 王汉[1] 

机构地区：[1]湖北医药学院附属襄阳医院神经内科,湖北襄阳441000

出　　处：《湖北医药学院学报》2013年第1期57-59,共3页Journal of Hubei University of Medicine

摘　　要：目的:观察神经损伤诊断治疗系统定位联合超声引导下注射A型肉毒毒素治疗脑卒中肌肉痉挛的临床疗效。方法:将我院2008年1月至2010年1月间收治的105例脑中卒痉挛患者随机分为对照组(n=50)和观察组(n=55),对照组患者采取常规康复治疗,观察组在此基础上采取神经损伤诊断治疗系统定位联合超声引导下注射A型肉毒毒素治疗,分析比较两组疗效。结果:两组患者在治疗1月后FMA、BBS和FIM明显改善,观察组在治疗后3、6个月的CSI、FMA、BBS及FIM评分改善情况优于对照组,差异有统计学意义(P<0.05)。结论:神经损伤诊断治疗系统定位联合超声引导下注射A型肉毒毒素治疗脑卒中肌肉痉挛效果显著,患者身体机能恢复快,值得临床推广。Objective To observe the effects of type A botulinum toxin injection under combined guidance of nerve injury diagnosis and treatment system and ultrasound in the treatment of patients with cerebral stroke spasm.Methods From January 2008 to January 2010,the clinical data of 105 patients with cerebral stroke spasm were collected,and then randomly divided into control group(n=50) and observation group(n=55).All patients were given regular rehabilitation therapy,meanwhile,the patients of observation group were given type A botulinum toxin injection under combined guidance of nerve injury diagnosis and treatment system and ultrasound in addition.The clinical curative effects were compared between two groups.Results The FMA,BBS and FIM were significantly improved in both two groups after treating for one month.The improvement degree of CSI,FMA,BBS and FIM scores in observation group were obviously superior to that in control group after treating for 3 and 6 months(P<0.05).Conclusion The type A botulinum toxin injection under combined guidance of nerve injury diagnosis and treatment system and ultrasound was effective in treatment of patients with cerebral stroke spasm,which was helpful for the recovery of body function and worthy of wide application.

关 键 词：脑卒中痉挛 系统定位 超声引导 A型肉毒毒素 临床疗效 

分 类 号：R743[医药卫生—神经病学与精神病学]