^(11)C蛋氨酸PET/CT与MRI对脑胶质瘤术前诊断价值的比较研究  

Comparison of ^(11)C-MET PET/CT and MRI for the diagnosis of gliomas before operation

作　　者：王如[1] 钱立庭[2] 汪世存[1] 展凤麟[1] 潘博[1] 张红雁[1] 马军[1] 

机构地区：[1]安徽医科大学附属省立医院,安徽合肥230001 [2]安徽医科大学附属省立医院肿瘤放疗科,安徽合肥230001

出　　处：《中国临床医学影像杂志》2012年第11期766-768,772,共4页Journal of China Clinic Medical Imaging

基　　金：安徽省科技攻关计划项目(07010302202)

摘　　要：目的:探讨11C-MET PET/CT对脑胶质瘤的术前诊断价值。方法:11例经MRI检查后拟诊胶质瘤的术前患者接受11C-MET PET/CT检查,将结果与术后病理比较。结果:11例患者中,1例术后病理为胶质细胞增生,其余10例均确诊为胶质瘤。11C-MET PET/CT与MRI在术前诊断脑胶质瘤的敏感性、特异性和准确性分别为100%、100%、100%和100%、0、91%。结论:11C-MET PET/CT对脑胶质瘤的术前诊断价值优于MRI。Objective: To evaluate the value of 11C-MET PET/CT and MRI for the diagnosis of gliomas before operation.Methods: We examined 11 patients prospectively with newly diagnosed gliomas based on brain MRI before operations.11CMET PET/CT was performed on these patients and then compared with their histological analysis.Results: Of all the eleven patients,ten were confirmed to be gliomas,except one glial cell hyperplasia.The sensitivity,specificity and accuracy of 11CMET PET/CT and MRI for diagnosis of gliomas before operation were 100%,100%,100% and 100%,0,91%,respectively.Conclusion: 11C-MET PET/CT is more helpful than MRI for diagnosis of gliomas before operation.

关 键 词：神经胶质瘤 脑肿瘤 正电子发射断层显像术 磁共振成像 

分 类 号：R730.264[医药卫生—肿瘤] R739.41[医药卫生—临床医学] R817.4R445.2