2-(3,5-二硝基苯)-4-硝基三唑-1-氧化物的合成及表征  

Synthesis and Characterization of 2-(3,5-Dinitrophenyl)-4-nitro-1,2,3-triazole-1-oxide

作　　者：杨威[1] 王伯周[1] 李亚南[1] 周诚[1] 王友兵[1] 

机构地区：[1]西安近代化学研究所,陕西西安710065

出　　处：《精细化工中间体》2012年第4期70-72,共3页Fine Chemical Intermediates

摘　　要：以乙二醛、苯肼和盐酸羟胺为起始原料,经缩合、肟化,生成中间体肟基苯腙,加入硫酸铜-吡啶-水体系,缩合环化得到2-苯基三唑-1-氧化物(PTO),然后硝硫混酸硝化合成了2-(3,5-二硝基苯)-4-硝基三唑-1-氧化物(TNPTO),总收率45%,中间体和TNPTO均通过红外光谱、核磁、质谱以及元素分析等进行了结构表征。初步探讨了铜盐作用下合成三唑环的反应机理。Starting from glyoxal,phenylhydrazine and hydrochloride hydroxylamine,2-(3,5-dinitrophenyl)-4-nitro-1,2,3-triazole-1-oxide(TNPTO)was synthesized by the processes of condensation,oximation,cyclization and nitration in overall yield of 45% and purity of 99%.The target compound and its intermediates were characterized with IR,1H NMR and elemental analysis.The reaction mechanism of cyclization in the solution of cupric sulphate-pyridine-water was proposed.

关 键 词：有机化学 合成 2-苯基三唑-1-氧化物 2-(3 5-二硝基苯)-4-硝基三唑-1-氧化物 

分 类 号：TJ55[兵器科学与技术—军事化学与烟火技术] O626[理学—有机化学]