含1,3,4-噻二唑的噻吩类化合物的合成与杀菌活性研究  

Synthesis and Biological Activity of Thiophene Derivatives Containing 1,3,4- Thiadiazol

作　　者：葛成林[1] 欧阳贵平[1] 贺宝安[1] 李飞飞[1] 

机构地区：[1]贵州大学精细化工研究开发中心,贵州贵阳550025

出　　处：《精细化工中间体》2012年第6期17-21,共5页Fine Chemical Intermediates

摘　　要：设计并合成了8个未见报道的含1,3,4-噻二唑的噻吩类化合物6a^6h,其结构经1H NMR、13C NMR、MS、IR分析确证。初步生物测试结果表明:目标化合物对黄瓜灰霉病、水稻纹枯病、马铃薯晚疫有一定的抑制作用。We have designed and synthesized eight novel thiophene derivatives containing 1,3,4-thiadiazol,and their structures were characterized by 1H NMR,13C NMR,MS,IR.Preliminary biological activity test indicated that some of them showed good inhibitory activity on Borrytis cinerea,Rhizoctonia solani and Phytophthora infestans.

关 键 词：1 3 4-噻二唑 酰胺 噻吩 抑菌活性 

分 类 号：TQ251.2[化学工程—有机化工]