脑电生物反馈对脑梗死患者D-二聚体的影响  

Effects of neurofeedback on the level of D-dimer in patients with cerebral infarction

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作  者:刘文杰[1] 胡义奎[1] 

机构地区:[1]武汉市普爱医院神经内科,湖北省武汉市430034

出  处:《实用老年医学》2013年第2期151-152,156,共3页Practical Geriatrics

摘  要:目的探讨超脑电生物反馈对脑梗死患者的纤溶系统指标D-二聚体(D-dimer)的影响。方法共选取发病72h内入院的急性脑梗死患者126例,运用随机数字表法分为脑电生物反馈治疗组(治疗组)62例及常规治疗组(对照组)64例,2组患者均接受神经内科常规药物治疗,治疗组在常规治疗基础上给予脑电生物反馈治疗。所有患者在入院时及治疗2周后进行血浆D-二聚体的检测及美国国立卫生院卒中量表(NIHSS)评分。结果经2周治疗后,治疗组有效率(88.7%)明显优于常规治疗组(68.7%,P<0.05);2组患者入院时D-二聚体水平高于阴性对照组(P<0.05),2周后2组D-二聚体水平较入院时降低(P<0.05),且治疗组变化幅度较对照组显著(P<0.05)。结论脑电生物反馈治疗能下调D-二聚体,对脑梗死患者的神经功能有显著改善作用。Objective To investigate the effects of neurofeedback on the level of D-dimer in the patients with acute cerebral infarction. Methods All 126 patients with cerebral infarction within the first 72 h from stroke onset were randomly divided into the control group(64 cases) and therapy group(62 cases). All patients received routine treatment, and the patients in therapy group were given additional neurofeedback. In both groups, the plasma level of D-dimer was measured by double antibodies sandwich enzyme linked immunosorbent assay(ELISA) at the time of admission and 2 weeks later. According to National Institute of Health Stroke Scale (NIHSS),the effect was evaluated at the time of admission and 2 weeks later. Results The score of NIHSS and the level of D-dimer were significantly decreased after therapy in both groups. The efficacy in therapy group was more significant than that in control group (88.7% vs 68.7%,P<0.05). Conclusions Neurofeedbak is effective in treating the acute cerebral infarction by decreasing the level of D-dimer.

关 键 词:脑电生物反馈 脑梗死 D-二聚体 

分 类 号:R743.3[医药卫生—神经病学与精神病学]

 

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