经支气管针吸活检在非小细胞肺癌术前淋巴结分期中的应用  

Role of transbronchial needle aspiration in lymph node staging of non-small-cell lung cancer before operation

作　　者：周燕娟[1] 周尧 姜敏炎[2] 薛志新[3] 仇铁峰[1] 朱小波[2] 凌夏君[1] 缪小辉[1] 蒋一雅[1] 钟亚花[1] 印秀丽[1] 庄志方[1] 

机构地区：[1]江苏大学附属武进医院呼吸科,江苏省常州市213002 [2]江苏大学附属武进医院胸外科,江苏省常州市213002 [3]江苏大学附属武进医院病理科,江苏省常州市213002

出　　处：《实用老年医学》2013年第5期424-426,共3页Practical Geriatrics

基　　金：江苏大学临床医学科技发展基金资助(JLY20100027)

摘　　要：目的探讨经支气管针吸活检(TBNA)在非小细胞肺癌(NSCLC)术前淋巴结分期中的临床应用价值和安全性。方法对术前胸部增强CT检查疑有纵隔/肺门淋巴结转移的26例NSCLC患者行TBNA检查,并与术后病理检查结果进行对比。结果 TBNA的敏感性、特异性、准确性、阳性预测值和阴性预测值,分别是76%(38/50)、100%(31/31)、85.2%(69/81)、100%(38/38)和72.1%(31/43)。病理分型总符合率为92.3%(24/26)。术前采用TBNA的c-N分期与p-N分期对比准确率可达92.3%(24/26)。全组无严重并发症发生。结论经TBNA进行NSCLC术前淋巴结分期,具有较高的临床实用价值和安全性。Objective To explore the role and safety of transbronchial needle aspiration(TBNA) in lymph node staging of non-small-cell lung cancer(NSCLC) before operation.Methods Twenty-six patients with NSCLC who were suspected mediastinal and/or hilar lymph node metastasis by contrast-enhanced computed tomography(CT) scaning underwent TBNA detection.The pathological results were compared with post-operative results.Results Overall diagnostic sensitivity,specificity,accuracy,positive predictive value and negative predictive value of TBNA for lymph node restaging were 76%(38/50),100%(31/31),85.2%(69/81),100%(38/38) and 72.1%(31/43) respectively.The overall coincidence rate of pathologic typing was 92.3%(24/26).The overall accuracy of c-N by TBNA was 92.3%(24/26) compared with p-N.Serious complications were not observed in all patients.Conclusions TBNA for lymph node staging of NSCLC is a safe method with high clinical application value.

关 键 词：经支气管针吸活检 非小细胞肺癌 淋巴结分期 

分 类 号：R734.2[医药卫生—肿瘤]