健康人群中筛查肺结节(早期肺癌)的敏感性与辐射剂量:GE VCT与GE 750 HDCT的纵向比较  

The sensitivity and radiation dose in pulmonary nodules (early-stage lung cancer) screening in healthy population: longitudinal comparison of GE VCT and GE 750 HDCT

作　　者：王迩诺[1] 高丰[1] 王园园[1] 李铭[1] 任庆国[1] 唐平[1] 滑炎卿[1] 

机构地区：[1]复旦大学附属华东医院放射科,上海200040

出　　处：《肿瘤影像学》2013年第1期9-13,共5页Oncoradiology

基　　金：上海市科委重点基金资助(No:10411952600)

摘　　要：目的比较GE VCT与GE 750 HDCT在健康人群中进行肺结节(早期肺癌)筛查的价值。方法对3 269例健康体检者肺部CT和临床资料进行分析,比较GE VCT与E 750 HDCT筛查早期肺癌的敏感性和辐射剂量。除探测器和重建算法外,其他软硬件和扫描参数均相同。结果 GE VCT组(931人)检出肺结节72例89个结节,病理证实早期肺癌3例;GE 750 HDCT组(605人)检出肺结节83例146个结节,病理证实早期肺癌4例。GE 750 HDCT对肺结节的检出率高于GE VCT(P<0.05)。GE VCT的CT容积剂量指数(CTDIvol)平均值为(9.820 9±1.630 92)mGy,剂量长度乘积(DLP)平均值为(511.15±45.73)mGy-cm;GE 750 HDCT的CTDIvol平均值为(5.425 0±1.721 08)mGy,DLP平均值为(229.09±84.73)mGy-cm。GE750 HDCT的辐射剂量低于GE VCT(P<0.05)。结论 GE 750 HDCT较VCT分辨率更高且辐射剂量更小,更适合健康群体早期肺癌的筛查。Objective To compare the value of GE VCT with GE 750 HDCT in pulmonary nodules(early lung cancer) screening in healthy population.Methods Based on the analysis of lung CT and clinical data of 3 269 healthy individuals,the sensitivity and radiation dose of GE VCT and GE 750 HDCT in detection of early lung cancer were compared.All the hardwares,softwares and scan parameters were the same except the detectors and reconstruction algorithms.Results In GE VCT group(931 cases),72 cases were detected with pulmonary nodules,and 3 cases were pathologically confirmed early-stage lung cancer.In GE 750 HDCT group(605 cases),83 cases were detected with pulmonary nodules,and 4 cases were pathologically confirmed early-stage lung cancer.The detection rate of GE 750 HDCT was higher than GE VCT(P<0.05).The average radiation dose in GE VCT group was(9.820 9±1.630 92) mGy,while in GE 750 HDCT was(5.425 0±1.721 08) mGy.There was significant difference between them(P<0.05).Conclusion The resolution of GE 750 HDCT is higher than GE VCT,but the radiation dose is lower.GE 750 HDCT is more suitable for early lung cancer screening in healthy population.

关 键 词：肺结节 早期肺癌 计算机断层摄影术 辐射剂量 

分 类 号：R734.2[医药卫生—肿瘤]