Chemical Constituents from Dried Aerial Parts of Eclipta prostrata  

作　　者：HAN Li-feng ZHAO Jing ZHANG Yi KOJO Agyemang LIU Er-wei WANG Tao 

机构地区：[1]Tianjin State Key Laboratory of Modern Chinese Medicine

出　　处：《Chinese Herbal Medicines》2013年第4期313-316,共4页中草药（英文版）

基　　金：Program for New Century Excellent Talents in University(NCET-10-0958);Important Drug Development Fund,Ministry of Science and Technology of China(2011ZX09307-002-01)

摘　　要：Abstract: Objective To study the constituents in the dried aerial parts of Eclipta prostrata. Methods The constituents wereisolated and purified by column chromatography and their structures were elucidated by spectroscopic methods (1D,2D NMR, UV, IR, and HRESI-TOF-MS) and chemical analyses. Results Eight compounds were isolated andidentified as 7-O-methylorobol-4′-O-β-D-glucopyranoside (1), 3′-hydroxybiochanin A (2), echinocystic acid28-O-β-D-glucopyranoside (3), ecliptasaponin A (4), eclalbasaponin I (5), eclalbasaponin IV (6), echinocystic acid(7), and 3-oxo-16α-hydroxy-olean-12-en-28-oic acid (8). Conclusion Compound 1 is a new compound andcompound 3 is obtained from this genus for the first time.Abstract: Objective To study the constituents in the dried aerial parts of Eclipta prostrata. Methods The constituents wereisolated and purified by column chromatography and their structures were elucidated by spectroscopic methods (1D,2D NMR, UV, IR, and HRESI-TOF-MS) and chemical analyses. Results Eight compounds were isolated andidentified as 7-O-methylorobol-4′-O-β-D-glucopyranoside (1), 3′-hydroxybiochanin A (2), echinocystic acid28-O-β-D-glucopyranoside (3), ecliptasaponin A (4), eclalbasaponin I (5), eclalbasaponin IV (6), echinocystic acid(7), and 3-oxo-16α-hydroxy-olean-12-en-28-oic acid (8). Conclusion Compound 1 is a new compound andcompound 3 is obtained from this genus for the first time.

关 键 词：COMPOSITAE Eclipta prostrata GLYCOSIDE isoflavonoid saponins 7-O-methylorobol-4′-O-β-D-glucopyranoside 

分 类 号：R284[医药卫生—中药学]