高b值扩散加权成像对前列腺癌的诊断价值  

High b-value diffusion weighted imaging in the diagnosis of prostate carcinoma

作　　者：刘丽琴[1] 叶靖[2] 肖芹[3] 孙峻[2] 李洁[2] 

机构地区：[1]江苏省苏北人民医院肿瘤科,江苏省扬州市225001 [2]江苏省苏北人民医院医学影像科,江苏省扬州市225001 [3]江苏省苏北人民医院病理科,江苏省扬州市225001

出　　处：《实用老年医学》2013年第10期850-852,共3页Practical Geriatrics

摘　　要：目的探讨高b值扩散加权成像对前列腺癌的诊断价值。方法经穿刺活检、手术病理证实的38例前列腺癌患者,回顾性分析其磁共振成像(MRI)特点并进行诊断。结果b=1000 s/mm2时检出ADC图对前列腺癌的敏感性为72%,特异性为89%,阳性预测值(PPV)为87%,阴性预测值(NPV)为67%;b=2000 s/mm2时分别为87%、92%、95%和75%。不同b值时磁共振扩散加权成像(DWI)对前列腺癌诊断的敏感性、PPV具有显著性差异。b=1000、2000 s/mm2时肿瘤组织的平均ADC值分别为1.17±0.38和0.75±0.19,与非肿瘤前列腺组织比较具有显著性差异(P<0.05)。结论常规MRI T2WI结合高b值DWI可显著提高前列腺癌的诊断准确性。Objective To retrospectively investigate the value of high b-value diffusion weighted imaging(DWI) in diagnosing prostate carcinoma.Methods Characteristics of prostate carcinoma in magnetic resonance imaging in 38 patients with pathology-proved prostate carcinoma were studied retrospectively Results The sensitivity,specificity,positive preditcive value(PPV) and negative predictive value(NPV) of DWI to prostate carcinoma was 72%,89%,87% and 67% when b = 1000 s / mm2,compared with 87%,92%,95% and 75% when b =2000 s/mm2.The apparent diffusion coefficient(ADC) value of tumor was 1.17 ± 0.38 or 0.75 ± 0.19 when b = 1000 or 2000 s/mm2.Conclusions High b-value DWI combined with T2WI can obviously improve the detecting accuracy of prostate carcinoma.

关 键 词：前列腺癌 磁共振成像 扩散加权成像 

分 类 号：R737.25[医药卫生—肿瘤]