控低温大剂量长脉冲激光治疗皮肤深部静脉畸形的临床研究  

Clinical Research of High Dose Long-pulsed Laser on Venous Malformations in Deep Skin Under the Condition of Controlling Low Temperature

作　　者：陈深[1] 严煜林[2] 韦妮波[2] 郑凤丽[2] 官英勇[3] 李伟强[1] 

机构地区：[1]广西医科大学第六附属医院口腔科,血管瘤专科门诊,广西玉林537000 [2]广西医科大学第一附属医院皮肤性病科,广西南宁530021 [3]广西医科大学第六附属医院麻醉科,血管瘤专科门诊,广西玉林537000

出　　处：《中国医疗美容》2014年第1期93-95,共3页China Medical Cosmetology

基　　金：广西科学自然基金(编号:2010GXNSFA013169);广西卫生厅医药卫生自筹经费计划课题(合同号Z2012736);广西卫生厅医药卫生自筹经费计划课题(合同号Z2013783);广西玉林市科技局基金项目(合同号玉市科攻12102043)

摘　　要：目的:探讨皮肤深部静脉畸形在瘤体控低温条件下应用长脉冲激光治疗的疗效和不良反应。方法:将皮肤深部静脉畸形分别采用常温和瘤体控低温条件下进行长脉冲激光治疗,观察两组瘤体在不同条件下其治疗效果和不良反应。结果:瘤体在控低温技术比常温下应用长脉冲激光治疗,其治疗剂量可以增大10~20 J/cm2,连续治疗强度和总能量可增大10倍,患者本人的痛觉感减轻,不良反应更少。经过8~10次治疗,治愈率为42%,显效率为33.33%,有效率为21.07%,总有效率为94.74%,不良反应率10.11%。结论:皮肤深部静脉畸形在瘤体控低温条件下可使用大剂量长脉冲激光治疗,疗效满意,痛苦少,不良反应少,宜在临床中推广使用。Objective:To explore the therapeutic effects and adverse reactions of high dose long-pulsed laser on venous malformation in deep skin under the condition of controlling low temperature. Method:Patients were divided into two groups,one group were treated with long-pulsed laser under usual temperature, and the other group were treated with long-pulsed laser under the conditions of controlling low temperature. Observing the therapeutic effect and adverse reaction of two groups under different conditions. Results:Compared with usual temperature,treatment dose can increase 10~20 J /cm2,continuous intensity of treatment and total energy can increase 10 times,pain and side effect were less under the condition of controlling low temperature. After 6 to 10 times of treatment,there were 42.00 percent of cure rate,33.33 percent of show efficiency rate,21.07 percent of effective rate,94.74 percent of the total effective rate and 10.11 percent of adverse reaction rate. Conclusion:Venous malformations in deep skin can be treated with high dose long-pulsed laser under the condition of controlling low temperature. It can improve curative effect,and reduce pain and adverse reactions. So it should be widely used in clinic.

关 键 词：控低温技术 长脉冲激光 瘤态变 能量叠加效应 静脉畸形 

分 类 号：R739.5[医药卫生—肿瘤]