角膜内皮细胞形态学的研究进展  

Research progress on the morphology of corneal endothelial cells

作　　者：杜飞[1] 毕燕龙[1] 

机构地区：[1]同济大学附属同济医院眼科,上海200065

出　　处：《外科研究与新技术》2013年第2期113-118,共6页Surgical Research and New Technique

基　　金：国家自然科学基金(30973247)

摘　　要：正常人体内角膜内皮细胞(corneal endothelial cells,CEC)不可再生,损伤后由临近细胞通过扩大、移行来填补空缺。CEC密度和形态是维持角膜正常结构、透明度及屈光指数的基本条件。外伤、手术或代谢问题均可能对其产生不可逆性的损伤。本综述对多种情况下CEC的形态学参数、功能状况、损伤修复等进行归纳整理,望对相关眼疾治疗及判断手术预后提供参考价值。The adult corneal endothelial cells ( CEC) could not take self-renewal. The circumjacent cells enlarge and migrate to fill the vacancy after trauma. A normal endothelial cellular density and morphology are pivotal to maintain a normal corneal structure,transparency and refractive index. Traumas,surgeries and some metabolic problems may lead to irreversible results. In this review ,the CEC morphological parameters,CEC function and redistribution in a variety of the situation were comprehensively reviewed. Hope it would provide a reference for the treatment of ocular diseases and the judgment of surgical prognosis.

关 键 词：角膜内皮细胞 形态学 屈光 密度 外伤 

分 类 号：R772.2[医药卫生—眼科]