老年实体肿瘤化疗耐受性研究  

Tolerance of chemotherapy in elderly patients with cancers

作　　者：翟树森[1] 王社论[1] 高云阁[1] 周学慧[1] 张瑞萍[1] 崔庆超[1] 董青[1] 雷琰[1] 

机构地区：[1]解放军306医院血液肿瘤科,北京100101

出　　处：《总装备部医学学报》2013年第3期141-143,共3页Medical Journal of General Equipment Headquarters

摘　　要：目的研究老年实体肿瘤患者对化疗的耐受性。方法回顾性分析我科老年实体肿瘤35例与中青年实体肿瘤47例化疗后的毒副反应,根据世界卫生组织(WHO)抗癌药物常见毒副反应分级标准评定毒副反应程度,并将老年实体肿瘤与中青年实体肿瘤患者化疗后毒副反应进行比较。结果老年实体肿瘤患者化疗后骨髓抑制、恶心呕吐、神经毒性反应与中青年患者比较,差异无统计学意义(χ2=3.0408~8.5446,P】0.05)。结论老年实体肿瘤患者能够耐受多数化疗的毒性反应。Objective To study the tolerance of chemotherapy for tumor in elderly patients. Methods According to the WHO chemotherapy drugs toxicity grading standards,the side effects of chemotherapy in 35 elderly and 47 middle-aged patients were analyzed retrospectively. Results There was no significant difference in bone marrow suppression,nausea/vomiting,neurotoxicity between the elderly patients group and the middle aged patients group. Conclusion The elderly cancer patients can tolerate the most toxicities of chemotherapy.

关 键 词：老年实体肿瘤 化疗 耐受性 毒副反应 

分 类 号：R730.53[医药卫生—肿瘤]