First Pillcam Colon 2 capsule images of Whipple's disease:Case report and review of the literature  

作　　者：Bogdan Radu Mateescu Andreea Bengus Madalina Marinescu Florica Staniceanu Gianina Micu Lucian Negreanu 

机构地区：[1]Department of Gastroenterology,Colentina Hospital [2]Department of Pathology,Colentina Hospital [3]Department of Internal Medicine 2-Gastroenterology,University Hospital

出　　处：《World Journal of Gastrointestinal Endoscopy》2012年第12期575-578,共4页世界胃肠内镜杂志（英文版）（电子版）

基　　金：Supported by ESGE-Given research grant 2010

摘　　要：Whipple's disease is a rare chronic systemic infection determined by the Gram-positive bacillus Tropheryma whipplei.The infection usually mainly involves the small bowel,but sometimes other organs are affected as well.Since the current standard clinical and biological tests are nonspecific,diagnosis is very difficult and relies on histopathology.Here we present the case of a 52-yearold man with chronic diarrhea and weight loss whose symptoms had been evolving for 2 years and whose diagnosis came unexpectedly after capsule examination.Diagnosis was confirmed by the histopathologic examination of endoscopic biopsy samples,and treatment with co-trimoxazole resulted in remission of symptoms.We present the first images of Whipple's disease obtained with the Pillcam Colon 2 video capsule system.Whipple’s disease is a rare chronic systemic infection determined by the Gram-positive bacillus Tropheryma whipplei. The infection usually mainly involves the small bowel, but sometimes other organs are affected as well. Since the current standard clinical and biological tests are nonspecific, diagnosis is very difficult and relies on histopathology. Here we present the case of a 52-year-old man with chronic diarrhea and weight loss whose symptoms had been evolving for 2 years and whose diagnosis came unexpectedly after capsule examination. Diagnosis was confirmed by the histopathologic examination of endoscopic biopsy samples, and treatment with co-trimoxazole resulted in remission of symptoms. We present the first images of Whipple’s disease obtained with the Pillcam Colon 2 video capsule system.

关 键 词：Whipple’s DISEASE MALABSORPTION CAPSULE ENDOSCOPY Pillcam COLON 2 

分 类 号：R516[医药卫生—内科学]