Drugs to be avoided in patients with long QT syndrome:Focus on the anaesthesiological management  

作　　者：Giovanni Fazio Federica Vernuccio Giuseppe Grutta Giuseppe Lo Re 

机构地区：[1]Poliambulatorio medico Riabiliter S.N.C.,Via Oreto,90124 Palermo,Italy [2]University of Palermo,90124 Palermo,Italy

出　　处：《World Journal of Cardiology》2013年第4期87-93,共7页世界心脏病学杂志（英文版）（电子版）

摘　　要：Long QT syndrome incidence is increasing in general population.A careful pre-,peri-and post-operative management is needed for patients with this syndrome because of the risk of Torsades de Pointes and malignant arrhythmias.The available data regarding prevention of lethal Torsades de Pointes during anesthesia in patients with long QT syndrome is scant and conflicting:only case reports and small case series with different outcomes have been published.Actually,there are no definitive guidelines on pre-,peri-and post-operative anesthetic management of congenital long QT syndrome.Our review focuses on anesthetic recommendations for patients diagnosed with congenital long QT syndrome furnishing some key points for preoperative optimization,intraoperative anesthetic agents and postoperative care plan,which could be the best for patients with c-long QT syndrome who undergo surgery.Long QT syndrome incidence is increasing in general population.A careful pre-,peri-and post-operative management is needed for patients with this syndrome because of the risk of Torsades de Pointes and malignant arrhythmias.The available data regarding prevention of lethal Torsades de Pointes during anesthesia in patients with long QT syndrome is scant and conflicting:only case reports and small case series with different outcomes have been published.Actually,there are no definitive guidelines on pre-,peri-and post-operative anesthetic management of congenital long QT syndrome.Our review focuses on anesthetic recommendations for patients diagnosed with congenital long QT syndrome furnishing some key points for preoperative optimization,intraoperative anesthetic agents and postoperative care plan,which could be the best for patients with c-long QT syndrome who undergo surgery.

关 键 词：Long QT Syndrome Torsades de POINTES ANESTHESIA QT-prolongation ANESTHETIC DRUGS 

分 类 号：R614[医药卫生—麻醉学]