A case of advanced mycosis fungoides with comprehensive skin and visceral organs metastasis:sensitive to chemical and biological therapy  

作　　者：Yi-Qian Liu Wei-You Zhu Yong-Qian Shu Yan-Hong Gu 

机构地区：[1]Department of Oncology,the First Affiliated Hospital of Nanjing Medical University

出　　处：《Asian Pacific Journal of Tropical Medicine》2012年第8期669-672,共4页亚太热带医药杂志（英文版）

基　　金：supported by the Jiangsu province Natural Science Foundation of China(No.BK2010579)

摘　　要：Mycosis fungoides is a common cutaneous T-cell lymphoma,which is usually characterized by chronic,indolence progression,with absence of typical symptoms in early stage,metastasis to lymph nodes,bone marrow and visceral organs in later stage and ultimately progression to systemic lymphoma.It can result in secondary skin infection which is a frequent cause of death. At present,no curative therapy existed.Therapeutic purpose is to induce remission,reduce tumor burden and protect immune function of patients.A case of patient with advanced severe mycosis fungoides receiving CHOP plus interferon a -2a was reported here,with disease-free survival of 7 months and overall survival of over 17.0 months,and current status as well as developments of mycosis fungoides were briefly introduced.Mycosis fungoides is a common cutaneous T-cell lymphoma,which is usually characterized by chronic,indolence progression,with absence of typical symptoms in early stage,metastasis to lymph nodes,bone marrow and visceral organs in later stage and ultimately progression to systemic lymphoma.It can result in secondary skin infection which is a frequent cause of death. At present,no curative therapy existed.Therapeutic purpose is to induce remission,reduce tumor burden and protect immune function of patients.A case of patient with advanced severe mycosis fungoides receiving CHOP plus interferon a -2a was reported here,with disease-free survival of 7 months and overall survival of over 17.0 months,and current status as well as developments of mycosis fungoides were briefly introduced.

关 键 词：MYCOSIS fungoides CUTANEOUS T-CELL LYMPHOMA Chemotherapy 

分 类 号：R519[医药卫生—内科学]