Increased serum nitric oxide and malondialdehyde levels in patients with acute intestinal amebiasis  

作　　者：Namiduru ES Tarakcloglu M Namiduru M Kocabas R Erbagcl B Meram I Karaoglan I Yilmaz N Cekmen M 

机构地区：[1]University of Gaziantep,Faculty of Medicine,Department of Biochemistry [2]University of Gaziantep,Faculty of Medicine,Department of Infectious Disease

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2011年第6期478-481,共4页亚太热带生物医学杂志（英文版）

基　　金：Supported by Scientific Research Projects Governing Unit ofGaziantep University(No.TF:00 04)

摘　　要：Objective:To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis.Methods:Twenty-four acute intestinal amebiasis patients and 20 healthy controls were enrolled in the present study.Serum malondialdehyde and nitric oxide levels were determined spectrophotometrically.Results:Serum raalondialdehyde and nitric oxide levels were significantly higher in acute intestinal amebiasis patients than healthy controls(P<0.00l). Conclusions:These results suggest that oxidative and nitrosative stress may play a major role in tissue damage in acute intestinal amebiasis patients.Also these parameters can be used to supplement the conventional microscopic method for reliable diagnosis of intestinal amebiasis.Objective:To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis.Methods:Twenty-four acute intestinal amebiasis patients and 20 healthy controls were enrolled in the present study.Serum malondialdehyde and nitric oxide levels were determined spectrophotometrically.Results:Serum raalondialdehyde and nitric oxide levels were significantly higher in acute intestinal amebiasis patients than healthy controls(P<0.00l). Conclusions:These results suggest that oxidative and nitrosative stress may play a major role in tissue damage in acute intestinal amebiasis patients.Also these parameters can be used to supplement the conventional microscopic method for reliable diagnosis of intestinal amebiasis.

关 键 词：AMEBIASIS MALONDIALDEHYDE NITRIC oxide 

分 类 号：R574[医药卫生—消化系统]