冷循环射频消融术联合肝动脉栓塞治疗肝脏肿瘤的临床研究  

Clinical Study of Radiofrequency Ablation Combined with Transcatheter Hepatic Arterial Chemoembolization for Hepatic Carcinoma

作　　者：张宇[1] 周文蓉[1] 张晓敏[1] 何建军[1] 李富秀[1] 

机构地区：[1]青海红十字医院,810000

出　　处：《实用癌症杂志》2014年第1期72-74,共3页The Practical Journal of Cancer

摘　　要：目的评价肝动脉化疗栓塞术(TACE)联合冷循环射频消融术(RFA)治疗肝脏肿瘤的临床疗效。方法 61例肝脏肿瘤分为单纯TACE治疗组(34例)和TACE联合冷循环射频消融术治疗组(27例)。治疗后行DSA、CT、超声检查及血清甲胎蛋白(AFP)测定。结果单纯TACE组肿瘤有效率、AFP下降率、1年生存率分别为52.9%、38.2%和48.4%,TACE+RFA联合组分别为85.2%、59.3%和79.4%,两组比较差异有统计学意义(P<0.05)。结论 TACE+RFA较单纯TACE治疗中晚期肝癌效果好,是治疗中晚期肝癌的一种有效方法,有较高的临床推广价值。Objective To evaluate the clinical value of radiofrequency ablation (RFA) combined with transcatheter he-patic arterial chemoembolization ( TACE) on hepatic carcinoma .Methods 61 patients with primary liver cancer were divided into two groups:34 cases were treated with TACE alone and 27 cases were treated with TACE combined with RFA .To evaluate the ef-ficacy with DSA、CT、ultrasound and serum alpha-fetoprotein (AFP) after treatment.Results The tumor efficiency、relapse rate and 1-year survival rates of TACE group were 52.9%、38.2%、48.4%respectively,and those of the TACE +RFA combination group were 85.2%、59.3% and 79.4%respectively,and there was statistical differences between the two groups (P<0.05). Conclusion Compared with TACE ,TACE +RFA is effective for advanced liver cancer .It is an effective method for the treat-ment of advanced hepatocellular carcinoma ,and has high clinical value .

关 键 词：肝癌 肝动脉化疗栓塞术 射频消融 

分 类 号：R735.7[医药卫生—肿瘤]