颅底脑膜瘤骨增生与骨侵袭的相关性研究  

Relevent Study of Meningioma of Cranial Base Hyperostosis Associated with Tumor Invasion

作　　者：步星耀[1] 胡明伟[2] 张永福[1] 李太平[1] 梁庆华[1] 王勇[1] 薛绛宇[1] 

机构地区：[1]河南省人民医院,郑州市450003 [2]郑州大学医学院

出　　处：《医药论坛杂志》2004年第13期11-12,16,共3页Journal of Medical Forum

基　　金：河南省杰出青年科学基金课题 (No :99)

摘　　要：目的　探讨颅底脑膜瘤骨增生与骨侵袭的关系。方法　选取 6 0例需手术治疗的颅底脑膜瘤患者 ,术前均行CT检查 ,确定骨质增生的程度与部位 ;术中将肿瘤连同骨质增生进行病理检查 ,确定有无脑膜瘤细胞骨侵袭。结果　CT证实的 34例有骨增生的颅底脑膜瘤患者 ,进行增生骨质活检有肿瘤细胞侵袭者 31例。结论　颅底脑膜瘤骨增生与肿瘤细胞骨侵袭有关 ,手术时应予充分切除。Objective To investigate the hyperostotic changes in meningioma of the cranial base associated with tumor invasion. Methods 60 patients underwent resection for meningioma involving the cranial base. Preoperative radiographic evaluation using computed tomography (CT) was performed, and areas of hyperostosis were identified. During the resection of the tumor, biopsies from these hyperostotic regions were sent for histological evaluation regarding the presence or absence of tumor invasion of the bone. Results Preoperative neuroradiological assessment by CT identified 34 patients with radiographic evidence of hyperostosis. Histological examination of the resected bone showed tumor invasion in 31 patients.Conclusion Hyperostotic changes in meningioma of the cranial base are caused by tumor invasion of the bone histologically.

关 键 词：脑膜瘤 颅底 骨增生骨 侵袭 

分 类 号：R739.41[医药卫生—肿瘤]