Recent developments in intelligent biomedical polymers  

作　　者：XIAO ChunSheng TIAN HuaYu ZHUANG XiuLi CHEN XueSi JING XiaBin 

机构地区：[1]State Key Laboratory of Polymer Physics and Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China [2]Graduate University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Science China Chemistry》2009年第2期117-130,共14页中国科学（化学英文版）

基　　金：Supported by the National Natural Science Foundation of China (Grant Nos.20604028, 50573078, and 50733003);National Fund for Distinguished Young Scholar (Grant No. 50425309);A3 Foresight Program of the National Natural Science Foundation of China (Grant No. 20621140369);Key International Science and Technology Cooperation Project of Ministry of Science and Technology of China (Grant No. 20071314)

摘　　要：Intelligent polymers or stimuli-responsive polymers may exhibit distinct transitions in physical-chemical properties, including conformation, polarity, phase structure and chemical composition in response to changes in environmental stimuli. Due to their unique 'intelligent' characteristics, stimuli-sensitive polymers have found a wide variety of applications in biomedical and nanotechnological fields. This review focuses on the recent developments in biomedical application of intelligent polymer systems, such as intelligent hydrogel systems, intelligent drug delivery systems and intelligent molecular recognition systems. Also, the possible future directions for the application of these intelligent polymer systems in the biomedical field are presented.Intelligent polymers or stimuli-responsive polymers may exhibit distinct transitions in physical-chemical properties, including conformation, polarity, phase structure and chemical composition in response to changes in environmental stimuli. Due to their unique ‘intelligent’ characteristics, stimuli-sensitive polymers have found a wide variety of applications in biomedical and nanotechnological fields. This review focuses on the recent developments in biomedical application of intelligent polymer systems, such as intelligent hydrogel systems, intelligent drug delivery systems and intelligent molecular recognition systems. Also, the possible future directions for the application of these intelligent polymer systems in the biomedical field are presented.

关 键 词：stimuli response INTELLIGENT POLYMERS HYDROGELS DRUG delivery systems molecular recognition 

分 类 号：O631.3[理学—高分子化学]