Stimulus-responsive polymeric nanoparticles for biomedical applications  被引量:11

Stimulus-responsive polymeric nanoparticles for biomedical applications

在线阅读下载全文

作  者:LI YongYong1,2,DONG HaiQing1,2,WANG Kang1,SHI DongLu 2,ZHANG XianZheng1 & ZHUO RenXi1 1Key Laboratory of Biomedical Polymers,Ministry of Education Department of Chemistry,Wuhan University,Wuhan 430072,China 2Institute for Advanced Materials and Nano Biomedicine(iNANO),Tongji University,Shanghai 200092,China 

出  处:《Science China Chemistry》2010年第3期447-457,共11页中国科学(化学英文版)

基  金:supported by the National Key Basic Research Program of China (Grant No 2005CB623903);the National Natural Science Foundation of China (Grant No 50633020);the Program for Young Excellent Talents in Tongji University,the Special Project of Shanghai Nanotechnology (Grant No 0952nm04800);Natural Science Foundation of Shanghai (Grant No 10ZR1432100)

摘  要:Polymeric nanoparticles with unique properties are regarded as the most promising materials for biomedical applications including drug delivery and in vitro/in vivo imaging.Among them,stimulus-responsive polymeric nanoparticles,usually termed as "intelligent" nanoparticles,could undergo structure,shape,and property changes after being exposed to external signals including pH,temperature,magnetic field,and light,which could be used to modulate the macroscopical behavior of the nanoparticles.This paper reviews the recent progress in stimulus-responsive nanoparticles used for drug delivery and in vitro/in vivo imaging,with an emphasis on double/multiple stimulus-responsive systems and their biomedical applications.Polymeric nanoparticles with unique properties are regarded as the most promising materials for biomedical applications including drug delivery and in vitro/in vivo imaging.Among them,stimulus-responsive polymeric nanoparticles,usually termed as "intelligent" nanoparticles,could undergo structure,shape,and property changes after being exposed to external signals including pH,temperature,magnetic field,and light,which could be used to modulate the macroscopical behavior of the nanoparticles.This paper reviews the recent progress in stimulus-responsive nanoparticles used for drug delivery and in vitro/in vivo imaging,with an emphasis on double/multiple stimulus-responsive systems and their biomedical applications.

关 键 词:polymer stimulus-responsive nanoparticles DRUG CARRIER cellular imaging 

分 类 号:R318.08[医药卫生—生物医学工程]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象