Oligo(ethylene glycol)-terminated monolayers on silicon surfaces and their nanopatterning with a conductive atomic force microscope  

作　　者：QIN GuoTing & CAI ChengZhi Department of Chemistry,University of Houston,Houston,Texas 77204,USA 

出　　处：《Science China Chemistry》2010年第1期36-44,共9页中国科学（化学英文版）

基　　金：supported by the Welch Foundation grant E-1498;NSF CAREER Award (CTS-0349228 to CC);grant DMR-0706627;NIH R21 HD058985

摘　　要：Functionalization of silicon substrate surfaces with a stable monolayer for resisting non-specific adsorption of proteins has attracted great interest,since it is directly relevant to the development of miniature,silicon-based biosensors and implantable microdevices,such as silicon-neuron interfaces.This brief review summarizes our contribution to the development of robust monolayers grown by surface hydrosilylation on atomically flat,hydrogen-terminated silicon surfaces.The review also outlines our strategy and progress on the fabrication of single molecule patterns on such monolayer platforms.Functionalization of silicon substrate surfaces with a stable monolayer for resisting non-specific adsorption of proteins has attracted great interest,since it is directly relevant to the development of miniature,silicon-based biosensors and implantable microdevices,such as silicon-neuron interfaces.This brief review summarizes our contribution to the development of robust monolayers grown by surface hydrosilylation on atomically flat,hydrogen-terminated silicon surfaces.The review also outlines our strategy and progress on the fabrication of single molecule patterns on such monolayer platforms.

关 键 词：protein-resistant monolayers surface HYDROSILYLATION CONDUCTIVE ATOMIC force MICROSCOPE NANOPATTERNING 

分 类 号：O621.2[理学—有机化学]