原发肾上腺淋巴瘤1例并文献复习  

Primary adrenal lymphoma: a case report and literature review

作　　者：沈权[1] 马洪杰[1] 任素梅[1] 袁红[1] 张振文[1] 

机构地区：[1]武警总医院,北京10069

出　　处：《现代生物医学进展》2009年第24期4689-4691,4704,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨原发肾上腺淋巴瘤(PAL)的临床特点,提高对该病的认识。方法:对1例原发肾上腺淋巴瘤患者的资料进行分析,并结合国内外相关文献进行总结。结果:原发肾上腺淋巴瘤好发于老年男性,可表现为局部症状如腹痛,腰痛,也可表现为乏力,发热,体重减低等全身症状,50%病人可出现肾上腺功能不全的症状。一些病人是在行影像学检查时因偶然发现肾上腺的肿物,经病理检查而确诊的。该病多累及双侧肾上腺,最常见的病理类型是弥漫大B细胞型。原发肾上腺淋巴瘤的治疗包括手术、化疗、放疗以及它们的不同组合。该病恶性程度高,进展迅速,预后差。结论:原发肾上腺淋巴瘤虽然少见,但在肾上腺肿瘤,尤其是快速增长的肾上腺肿瘤的鉴别诊断中应考虑到它的可能,及时进行病理检查可尽早确诊。Objective:To investigate the clinical features of primary adrenal lymphoma (PAL), and to improve the recongnization of PAL.Method:The clinical datum of one case of primary adrenal lymphoma was analyzed and the related literature was reviewed. Results: PAL generally affects elderly men, may prensent with local symptoms such as abdominal/lumbar pain or systemic symptoms such as fatigue,fever,weight loss.Symptoms of adrenal insufficiency are seen in 50% of patients with PAL.Still some adrenal masses are found incidentally on imaging.The definitive diagnostic of PAL depended on cytology of adrenal tissue.It's clinical features consist of a high incidence of bilateral adrenal involvement and diffuse large B-cell lymphoma.Treatments for PAL have included various combinations of surgery,chemotherapy,and radiation.PAL is a highly agressive disease and carries a poor prognosis.Concolusion: Primary adrenal lymphoma,although a rare entity, should be considered in the differential diagnosis for adrenal mass,especially a rapidly enlarging adrenal mass. A biopsy may be helpful for diagnosis .

关 键 词：淋巴瘤 肾上腺肿瘤 原发性 病理学 

分 类 号：R736.6[医药卫生—肿瘤]