CAD/CAM纯钛烤瓷冠修复前后龈沟液中碱性磷酸酶与肿瘤坏死因子-α的变化  

The change of ALP and TNF-α in gingival crevicular fluid before and after CAD/CAM pure titanium based PFM crown was worn

作　　者：张风华[1] 安雁鸣 杜晓燕[1] 

机构地区：[1]石家庄市第一医院口腔科,石家庄050011

出　　处：《中国实用口腔科杂志》2009年第2期97-98,共2页Chinese Journal of Practical Stomatology

基　　金：河北省科学技术厅指令性课题(08276101D-72)

摘　　要：目的探讨计算机辅助设计与制作(CAD/CAM)纯钛烤瓷冠修复对患牙牙周组织的影响。方法选择2008年1月至12月到石家庄市第一医院口腔科就诊的前磨牙有大面积牙体缺损患者20例(30颗牙),采用金属桩核加CAD/CAM纯钛烤瓷冠修复。在牙体预备前及修复体戴入后8个月,分别对龈沟液(GCF)量及GCF中碱性磷酸酶(ALP)活性及肿瘤坏死因子-α(TNF-α)质量浓度进行检测,并对检测结果进行分析比较。结果修复体边缘的深度及密合度均符合临床要求,修复后GCF量、ALP活性及TNF-α质量浓度与修复前比较差异无统计学意义(P>0.05)。结论短期内,临床合格的纯钛烤瓷冠对牙周组织未产生明显不利影响。Objective To detect the effects of CAD/CAM pure Titanium based PFM crown on the periodontal tissue of the restored teeth.Methods Twenty clinical patients were randomly selected from the patients who came to the Department of Stomotology of the First Hospital of Shijiazhuang,with 30 premolars with a large area destruction of crowns.We used CAD/CAM pure Titanium based PFM crown combined with metal caryopivot to restore them.Before teeth preparation and 8 months after the placement of the crowns,the weight of GCF and the level of GCF-ALP and the concentration of TNF-αin gingival crevicular fluid were checked,the results analyzed statistically.Results Restoration marginal depth and fitness were all consistent with clinical requirement.The weight of GCF,the level of ALP and concentration of TNF-αin gingival crevicular fluid before and after operation had no significant statistical difference(P>0.05).Conclusion In short term,pure Titanium based PFM crown clinically qualified has no significantly negative influence on gingival health of the restored teeth.

关 键 词：纯钛烤瓷冠 龈沟液 碱性磷酸酶 肿瘤坏死因子-Α 

分 类 号：R783[医药卫生—口腔医学]