牙髓卟啉单胞菌内毒素致病性研究进展  

Research progress on the pathogenicity of lipopolysaccharides extracted from Porphyromonas endodontalis

作　　者：李任[1] 仇丽鸿[1] 

机构地区：[1]中国医科大学口腔医学院口腔内科,沈阳110002

出　　处：《中国实用口腔科杂志》2009年第12期756-758,共3页Chinese Journal of Practical Stomatology

摘　　要：牙髓卟啉单胞菌是根尖周病变中的重要致病菌之一,牙髓卟啉单胞菌可产生多种毒力因子,其中内毒素尤为重要。研究证明,在根尖周病变的发展过程中,根尖部炎症反应以及骨吸收的发生等都与牙髓卟啉单胞菌内毒素密切相关。本文针对牙髓卟啉单胞菌内毒素的致病性研究进展加以综述。As one of the most important pathogenic bacteria,Porphyromonas endodontalis(P.e)could produce many kinds of virulence factor. Lipopolysaccharides (LPS) is one particularly important virulence factor. Researches showed that in the process of periapical disease,P.e-LPS is strongly associated with bone absorption and inflammatory response in lesions of apical periodontitis. Research progress on the pathogenicity of lipopolysaccharides extracted from Porphyromonas endodontalis were reviewed in this paper.

关 键 词：牙髓卟啉单胞菌 内毒素脂多糖 致病性 根尖周病变 

分 类 号：R78[医药卫生—口腔医学]