Molecular dynamics simulations investigation of Neocarzinostatin Chromophore releasing pathways from the Holo-NCS protein  

作　　者：Xi Zhao1, Song Wang1, Xue-feng Gao2, Xu-ri Huang1, Chia-chung Sun1 1 State Key Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun 130023, People’s Republic of China 2 College of L ife Science,Jilin University, Changchun 130023, People’s Republic of China 

出　　处：《生物物理学报》2009年第S1期377-377,共1页Acta Biophysica Sinica

摘　　要：The enediyne ring chromophore with strong DNA cleavage activity of neocarzinostatin is labile and therefore stabilization by forming the complex (carrying protein + chromophore:

关 键 词：Neocarzinostatin ENEDIYNE ring CHROMOPHORE release MOLECULAR DYNAMICS force-probe MOLECULAR DYNAMICS essential dynamics. 

分 类 号：Q6[生物学—生物物理学]