听觉诱发电位P50缺陷相关基因的研究进展  

Recent Advances of Auditory Evoked Potential P50 Defect Related Gene

作　　者：李伟[1] 袁颐捷[1] 何敏[1] 

机构地区：[1]昆明医学院生理教研室,云南昆明650031

出　　处：《昆明医科大学学报》2009年第S2期158-161,共4页Journal of Kunming Medical University

摘　　要：脑听觉诱发电位P50缺陷,是一系列神经精神疾病的共同特征,在对P50产生机制的探索过程中,尤其是对精神分裂症病人及其亲属的研究中发现,这种缺陷与遗传基因异常有很大关系.对近年来胆碱能受体基因、5-羟色胺受体基因和多巴胺D2受体基因的研究作一综述.Recent studies indicates brain stem auditory evoked potential P50 defect is a common character of a series of nervous and mental diseases.In search of how P50 generates,especially study on schizophrenia patients and their relatives,researchers discovered this kind of defect has close relationship with genetic gene abnormality.This text obtained the conclusion based on pertinent literature of domestic and overseas that,studies on this direction are focused on a7-Ach receptors gene,5-HT receptors gene and dopamine D2 receptors gene.

关 键 词：听觉诱发电位 P50 感觉门控 基因 

分 类 号：R749[医药卫生—神经病学与精神病学]