A New Type of Deaggregators, the Bolaamphiphilic DeAgrs. Observations of the Dependence of Deaggregating Ability on Aggregator Concentration and Solvent Aggregating Power  

作　　者：周其忠 史济良 蒋锡夔 黎占亭 

出　　处：《Chinese Journal of Chemistry》2002年第11期1279-1286,1129,共8页中国化学（英文版）

基　　金：NSFC (No .2 9832 0 40 )andStateKeyProjectofFundamentalResearch (No .G2 0 0 0 0 7810 1)

摘　　要：Four new amphiphilic molecules, i.e., the bolaamphiphiles n-trimethylamino n-hexadecanoate (deAgr 16), n-dodecanoate (deAgr 12), n-undecanoate (deAgr 11), and n-octanoate (deAgr 8) were synthesized. Their ability as deaggregators to break up the aggregating systems of hexadecyl β-naphthoate (A16) and dodecyl β-naphthoate (A12) in dioxanewater binary solvent systems was investigated in a number of solvent systems and at different A16 and A12 concentrations. The results reveal that this new type of bolaamphiphilic molecules appears to be one of the most efficient deaggregators reported, which, at very low concentrations, can effectively break up the aggregating systems of highly concentrated A16 and A12. It is also found that bolaamphiphfles with longer aliphatic chains possess greater deaggregating ability. However, when the overall concentrations of A16 and A12 are very low but still above their critical aggregating concentration, these bolaamphiphilic molecules lose their deaggregating power and tend to coaggregate with the aggregated A16 or A12 molecules. The quite efficient deaggregating ability of the long-chain bolaamphiphfles (deAgr 16 and deAgr 12), as compared to the short-chain deAgr 8, has been ascribed to their dynamic switch-on/switch-off behavior involving coiled-up and uncoiled conformations of their long aliphatic chains.Four new amphiphilic molecules, i.e., the bolaamphiphiles n-trimethylamino n-hexadecanoate (deAgr 16), n-dodecanoate (deAgr 12), n-undecanoate (deAgr 11), and n-octanoate (deAgr 8) were synthesized. Their ability as deaggregators to break up the aggregating systems of hexadecyl β-naphthoate (A16) and dodecyl β-naphthoate (A12) in dioxanewater binary solvent systems was investigated in a number of solvent systems and at different A16 and A12 concentrations. The results reveal that this new type of bolaamphiphilic molecules appears to be one of the most efficient deaggregators reported, which, at very low concentrations, can effectively break up the aggregating systems of highly concentrated A16 and A12. It is also found that bolaamphiphfles with longer aliphatic chains possess greater deaggregating ability. However, when the overall concentrations of A16 and A12 are very low but still above their critical aggregating concentration, these bolaamphiphilic molecules lose their deaggregating power and tend to coaggregate with the aggregated A16 or A12 molecules. The quite efficient deaggregating ability of the long-chain bolaamphiphfles (deAgr 16 and deAgr 12), as compared to the short-chain deAgr 8, has been ascribed to their dynamic switch-on/switch-off behavior involving coiled-up and uncoiled conformations of their long aliphatic chains.

关 键 词：DEAGGREGATION BOLAAMPHIPHILE AGGREGATION solvent aggregating power 

分 类 号：O621.2[理学—有机化学]