Asymmetric allylation of aldehydes and alkylation using "carbon-centered" chiral organosilicon compounds  

作　　者：王东 

出　　处：《Chinese Journal of Chemistry》1999年第5期429-437,425,共9页中国化学（英文版）

基　　金：National Natural Science Foundation of China.

摘　　要：The effects of the chiral substituents attached to silicon on the stereoselectivity of the reactions of C-centered chiral silicon compounds wm examined. The investigation was focused on the asymmetric C—C bond formation reaction of chiral allylsilanes and α-silylallyl anions with aldehydes. The functionalities of the substituents on silicon can be manipulated to improve the stereoselectivities of the reactions remote from silicon atom.The effects of the chiral substituents attached to silicon on the stereoselectivity of the reactions of C-centered chiral silicon compounds wm examined. The investigation was focused on the asymmetric C—C bond formation reaction of chiral allylsilanes and α-silylallyl anions with aldehydes. The functionalities of the substituents on silicon can be manipulated to improve the stereoselectivities of the reactions remote from silicon atom.

关 键 词：Carbon-centered chiral organosilicon compound asymmetric C—C bond formation reaction ALLYLSILANE α-silylallyl anion 

分 类 号：O621.2[理学—有机化学]