复方丹参抗突变作用研究  

STUDY ON ANTIMUTAGENIC OF SALVIA MILTIORRHIZA COMPUSITA

作　　者：王世英[1] 王卫东[1] 严镇钧[1] 李爱全 

机构地区：[1]湖北师范学院生物系,黄石435002

出　　处：《湖北师范学院学报（自然科学版）》1999年第2期18-20,共3页Journal of Hubei Normal University(Natural Science)

摘　　要：应用活体小鼠骨髓嗜多染红细胞（ＰＣＥ）微核试验，研究了中药复方丹参的遗传毒性和抗突变效应。结果表明，复方丹参无致突变性且对环磷酰胺诱发的遗传损伤有明显的抑制作用。The micronucleus in polychromatic erythrocytes (PCE) of mouse bone-marrow was counted for studying the genotoxicity and antimutagenic of Salvia miltiorrhiza composita. The results indicated that the Salvia miltiorrhiza composita showed obviously inhibitory effects on the genetic damage induced by Cyclophosphamide,and no mutagenicity.

关 键 词：复方丹参 维核试验 环磷酰胺 致突变性 抗突变 

分 类 号：R285[医药卫生—中药学]