肌萎缩侧索硬化低频电刺激时波幅的衰减  

DECREMENT OF AMPLITUDE TO REPETITIVE NERVE STIMULATION AT SLOW RATES IN AMYOTROPHIC LATERAL SCLEROSIS

作　　者：张为西[1] 吕建敏[1] 

机构地区：[1]中山医科大学附属第一医院神经科,510080

出　　处：《现代电生理学杂志》1998年第1期10-12,共3页Journal of Modern Electrophysiology

摘　　要：目的:为了探讨肌萎缩侧索硬化低频重复电刺激时波幅的变化。方法:运用丹麦丹迪公司生产的Countpoint肌电图机对30例肌萎缩侧索硬化患者及30例正常人进行低频重复电刺激的研究。结果:半数以上的患者波幅呈递减反应,波幅的衰减在有束颤及肌萎缩者明显,动作电位的低波幅与波幅的衰减率是呈相关。结论:肌萎缩侧索硬化存在神经肌肉接头损害。Objective:to explore the change of amplitude to repetitive nerve stimulation (RNS) at slow rates in amyotrophic lateral sclerosis (ALS).Methods:30 patients with ALS and 30 normal volunteers were given RNS test at slow rates by electromyography made in Dantec of demark.Results:at least half of patients with ALS had some degree of decrement of amplitude to RNS.Decremental responses are apparent in the patients with muscular alrophy and fasciculation.There was a negative correlation between lower amplitude and decrement of amplitude.Conclusions:there is functional alteration of neuromuscular junction in ALS.

关 键 词：肌萎缩侧索硬化 重复电刺激 

分 类 号：R746.4[医药卫生—神经病学与精神病学]