精神分裂症患者血清7种元素含量测定及分析  

An assay of the contents of 7 serumal elements in patients with schizophrenia

作　　者：吕士杰[1] 潘文干[1] 罗卫国[1] 罗军[1] 张晋春 宋德聚 

机构地区：[1]空军医学高等专科学校,吉林市132013 [2]长春市精神病医院,长春市132000 [3]空军后勤部血液制品研究所,郑州市450007

出　　处：《空军医高专学报》1997年第2期85-88,共4页

摘　　要：采用火焰原子吸收法测定精神分裂症患者28例(首次治疗病人16例,多次住院治疗病人12例)和健康对照者10例血清钠(Na)、钾(K),钙(Ca)、镁(Mg)、铁(Fe)、铜(Cu)、锌(Zn)的含量。结果表明,精神分裂症患者血清Ca、Mg、Cu、Zn含量显著低于对照组(P<0.05),并且首次治疗病人血清Mg、Zn含量降低程度较多次住院治疗者更明显(P<0.05)。相关分析患者组病人血清Zn与Ca、Mg与Ca 呈负直线相关。Seven elements (Na,K ,Ca,Mg,Fe,Cu,Zn) in serum of 28 cases of schizophrenia (16 cases were treated for the first time and 12 for more than once) were assessed with flame atomic absorption speotrophotometry and compared with those of 10 normal controls. The results showed that the contents of Ca,Mg,Cu,Zn in the serum of the patients were obviously lower than those of the controls (P< 0. 05),and the contents of Mg,Zn in serum of the first-treated patients were still lower than those of the repeatedly-treated ones(P<0. 01). The Cu/Zn ratio in the patients were higher than in the controls ( P < 0. 05). In the patients, a negative straight-line interrelation was shown between Zn and Ca and between Mg and Ca.

关 键 词：精神分裂症 化学元素 火焰原子吸收法 

分 类 号：R749.3[医药卫生—神经病学与精神病学]