An Immunohistochemical Study of IgG, Complement C_3, Collagen Type Ⅲ and Macrophage-Marker Ki-M_7 in Epiretinal Membranes  

作　　者：Yining Shi, Yannian Hui, Jixian MaDepartment of Ophthalmology, Xian Xijing Hospital The 4th Military Medical University, Xian 710032, China 

出　　处：《Eye Science》1996年第1期10-14,共5页眼科学报（英文版）

摘　　要：Purpose: To observe the immunological changes in epiretinal membranes from the patients with proliferative vitreoretinopathy (PVR).Methods: Twelve samples of epiretinal membranes obtained during vitreous surgeries for PVR were examined by direct and indirect immunofluorescein histochem-istry.Results: The cellular membranes in 8 cases were composed of retinal pigment epithelial cells, fibroblast-like cells, macrophages and collagen. Positive stainings of IgG. C3, collagen type 1 and macrophage-marker Ki-M7(CD68) was seen in the membranes.Conclusion : The results indicate that humoral immune components and macrophages may play an important role in the development of epiretinal membrane formation. Eye Science 1996; 12:10-14.Purpose: To observe the immunological changes in epiretinal membranes from the patients with proliferative vitreoretinopathy (PVR).Methods: Twelve samples of epiretinal membranes obtained during vitreous surgeries for PVR were examined by direct and indirect immunofluorescein histochem-istry.Results: The cellular membranes in 8 cases were composed of retinal pigment epithelial cells, fibroblast-like cells, macrophages and collagen. Positive stainings of IgG. C3, collagen type 1 and macrophage-marker Ki-M7(CD68) was seen in the membranes.Conclusion : The results indicate that humoral immune components and macrophages may play an important role in the development of epiretinal membrane formation. Eye Science 1996; 12:10-14.

关 键 词：retinal DETACHMENT PROLIFERATIVE VITREORETINOPATHY epiretinal membranes IMMUNOHISTOCHEMISTRY 

分 类 号：R770.3[医药卫生—眼科]