The　Observation　of　Complement　Activation　and　Polymorphonuclear　Neutrocytopenia　during　Cardiopulmonary　Bypass  

作　　者：汪东仿 傅平 蔡俊坚 蓝鸿钧 

出　　处：《Journal of Huazhong University of Science and Technology(Medical Sciences)》1996年第2期99-102,共4页华中科技大学学报（医学英德文版）

摘　　要：By determining the plasma levels of C3, C4, factor B and polymorphonuclear neutrophils (PMNs) of the patients who received CPB, the path of complement activation and changes of PMNs were studied. The results suggest that complement system was activated through alternative pathway during CPB and was activated through classic pathway after CPB. The anaphylatoxin, the products of complement activation may be responsible for the polymorphonuclear neutrocytopenia.By determining the plasma levels of C3, C4, factor B and polymorphonuclear neutrophils (PMNs) of the patients who received CPB, the path of complement activation and changes of PMNs were studied. The results suggest that complement system was activated through alternative pathway during CPB and was activated through classic pathway after CPB. The anaphylatoxin, the products of complement activation may be responsible for the polymorphonuclear neutrocytopenia.

关 键 词：cardiopulmonary bypass COMPLEMENT polymorphonuclear neutrophil 

分 类 号：R33-33[医药卫生—人体生理学]