形态测量对肝细胞肝癌分级的研究  

MORPHOMETRICAL ASSESSMENT FOR CLASSIFICATION OF DIFFERENT GRADES OF HEPATOCELLULAR CARCINOMA

作　　者：来茂德[1] 周水云[1] 陈培辉[1] 洪子福[1] 

机构地区：[1]浙江医科大学病理学教研室,浙江医科大学形态中心

出　　处：《中国组织化学与细胞化学杂志》1995年第2期175-179,共5页Chinese Journal of Histochemistry and Cytochemistry

摘　　要：应用自行设计组装的ＭＩＰＳ－Ｉ型多功能图像分析仪对６０例不同级的肝细胞肝癌细胞核形态学以及ＤＮＡ含量的９个参数进行了测定。经多元判别分析建立判别方程，发现９个参数都有判别能力。对判别方程贡献最大的四个参数依次为核面积、核平均光密度＞５Ｃ细胞百分数和核周长。回代符合率为９５％。parameters of cytological features and DNA content were measured in 60 cases of hepatocellular carcinomas with self-designed MIPS-I image analysis system.All parameterswere demonstrated to be useful for discrimination and classifiation among them.Foue parameters were showed to be the most important ones for discriminant equation.They were nuclear area, mean nuclear optic density,percentage of cells with more than 5C and nuclearPerimeter.95% of predicted cancers were correctly identified in different grades.

关 键 词：肝细胞肝癌 分级 形态定量 

分 类 号：R735.7[医药卫生—肿瘤]