Studies　on　the　Anti-atherosclerosis　Effects　of　Rhubarb　and　Salvia　Miltiorrhiza  

作　　者：范乐明 姜传昌 陈毓华 

出　　处：《The Journal of Biomedical Research》1994年第1期16-18,共3页生物医学研究杂志（英文版）

摘　　要：The effects of Rhubarb and Salvia Miltiorrhiza on serum lipids, aortic cholestercl contentand liver LDL receptor mRNA level in experimental rats were observed. The result showed that:(1)Rhuberb significantly decreased serum TC, LDL-C and aortic cholesterol content,which might be partlyattributed to its effect on LDL clearance by LDL receptor pathway.(2) Salvia Miltiorrhiza reduced moreeffectively the cholesterol accumulation in aorta,which might be due to its inhibition of endogenouscholesterol synthesis and anti-oxidative action.The effects of Rhubarb and Salvia Miltiorrhiza on serum lipids, aortic cholestercl contentand liver LDL receptor mRNA level in experimental rats were observed. The result showed that:(1)Rhuberb significantly decreased serum TC, LDL-C and aortic cholesterol content,which might be partlyattributed to its effect on LDL clearance by LDL receptor pathway.(2) Salvia Miltiorrhiza reduced moreeffectively the cholesterol accumulation in aorta,which might be due to its inhibition of endogenouscholesterol synthesis and anti-oxidative action.

关 键 词：ATHEROSCLEROSIS RHUBARB saliva miltiorrhiza 

分 类 号：R285.6[医药卫生—中药学]