低剂量安乐霉素联合化疗治疗白血病等血液肿瘤  

Low-Dose Aclacinomycin Combined Chemotherapy of Blood Tumors

作　　者：刘泽霖[1] 刘敏涓[1] 谭获[1] 彭中宜[2] 李国梁[2] 

机构地区：[1]广州医学院血液学研究室 [2]黑龙江省医院血液内科

出　　处：《广州医学院学报》1992年第3期51-53,共3页Academic Journal of Guangzhou Medical College

摘　　要：本文报告了用低剂量安乐霉素加长春新碱或阿糖胞苷组成联合化疗方案治疗各类血液肿瘤25例的临床疗效,ALL5例,AML14例,CML4例,MM1例,MH1例。安乐霉素总量100mg为一疗程。结果:CR44％(11/25),CR中4例(ALL2例,CML2例)为复治病例,表明安乐霉素与柔红霉素无交叉耐药性,PR40％(10/25),NR16％(4/25)。主要副作用为骨髓抑制及心肌受损。Clinical response and side effects of low-dose ACM combined VCR or Ara-C were studied in twenty-five patients with various blood tumors in this paper:ALL five cases,AML fourteen cases, CML four cases,MM one case,MH one case. A total dosage of ACM was refractory ALL or CML in complete remission, which suggests no cross-resistance between ACM and DNR. PR 40% (10/ 25). NR 16% (4/25). Major side effects were bone marrow suppression and cardiotoxicity.

关 键 词：低剂量安乐霉素 血液肿瘤 

分 类 号：R[医药卫生]