脑肿瘤与入白细胞抗原关系的探讨  

Primary Investigation of Relationship between Cerebral Tumor and Human Leuckocyte Antigens

作　　者：何旦莎[1] 曾白云[1] 邓维意[1] 王增慧[1] 蔡昭明[1] 

机构地区：[1]广州医学院神经科学研究所

出　　处：《广州医学院学报》1992年第1期10-13,共4页Academic Journal of Guangzhou Medical College

摘　　要：本文对广东省汉族正常人98例,脑肿瘤患者71例进行HLA-A,B,位点分型调查。通过对比分析,发现脑肿瘤组HLA-B_5和B_(w46)抗原频率显著高于正常人组,而B_(16)抗原频率则显著低于正常人组。其中29例胶质细胞瘤患者B_5抗原频率显著高于正常人组,B_(16)抗原频率显著低于正常人组。Ninety eight normal persons in Guangdong Province Han Population and seventy one patients with cerebral tumor were detected by means of HLA-A. B locus typing. Compared the typing results of patient group with control,we found that the frequences of HLA B_5and B_(w46)of patient groups were higher than that of control,the frequence of HLA B_(16) of patient group was lower than that of control. Twenty nine cases with glioma presented that frequency of HLAB_5 increased and frequence of HLAB_(16) decreased in contrast with normal control.

关 键 词：颅内肿瘤 人白细胞抗原 

分 类 号：R[医药卫生]